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White Button Mushrooms Show Promise in Prostate Cancer Treatment 

United States: Scientists at City of Hope, which is one of the largest and most well-equipped comprehensive cancer centers in the United States, offering a wide array of leading edge basic, clinical, and population services with dedicated integrated supportive care services for cancer patients and a national reputation for providing supportive care to its cancer patients have now ascertained why a white button mushroom supplements that under a clinical investigation demonstrate a potential to put a brake on both the progression and metastasis of prostate This discovery is part of a phase 2 clinical trial about the “food as medicine” approach, as reported by scitechdaily.com. 

Carrying out the previous research, the scientists from the City of Hope identified that white button mushroom pills lower a type of immune cells, which is connected to cancer formation and metastases, namely myeloid-derived suppressor cells (MDSCs) based on preclinical and pilot clinical data. 

Exploring the Potential of Plant-Derived Therapies 

“City of Hope researchers are investigating foods like white button mushroom, grape seed extract, pomegranate, blueberries, and ripe purple berries called Jamun for their potential medicinal properties. We’re finding that plant-derived substances may one day be used to support traditional cancer treatment and prevention practices,” said Shiuan Chen, Ph.D., the Lester M. and Irene C. Finkelstein Chair in Biology, professor and chair of the Department of Cancer Biology and Molecular Medicine at Beckman Research Institute of City of Hope, and senior author of the new Clinical and Translational Medicine study. 

“This study suggests that ‘food as medicine’ treatments could eventually become normal, evidence-based cancer care that is recommended for everyone touched by cancer.” 

Integrative oncology, which involves natural therapies for handling cancer diseases, is becoming popular with the increasing concern of people and their willingness to embrace the whole-person concept of cancer disease treatment. With the $100 million endowment provided by Pand Express Co-CEOs Andrew and Peggy Cherng, City of Hope’s Cherng Family Center for Integrative Oncology is expanding the knowledge, training, and application of patient-safe, evidence-based oncologic care. 

From the laboratory to the clinic 

Integrative bidirectional research consisting of physicians and lab researchers is possible at the City of Hope, and laboratory discoveries relating to cancer can be taken directly to the patients and the other way around to develop new fast-acting cancer treatments. 

Promising Results in Animal and Human Studies 

White button mushroom extract was also proven by the researchers to have the capacity to Halt tumor growth and prolong the lifespan of mice models. It also enhanced T cell immune response due to a decrease in MDSC levels in animal models, which refers to the ability of the immune system to kill cancer cells. 

The researchers sampled blood from some of the men in City of Hope’s phase 2 study group. The men were under observation as they consumed white button mushroom supplements. Before and after treating eight participants with three months of white button mushroom, the scientists were able to determine that there were fewer MDSCs that create tumors and more of the T and natural killer cells, which are anti-tumor in nature. It, therefore, means that the white button mushroom reconstructs the immune defense against cancer and decelerates the rate of growth of cancer cells, as reported by scitechdaily.com. 

Important Considerations for Supplement Use 

“Our study emphasizes the importance of seeking professional guidance to ensure safety and to avoid self-prescribing supplements without consulting a health care provider,” said Xiaoqiang Wang, M.D., Ph.D., City of Hope staff scientist and first author of the study. “Some people buy mushroom products or extract online, but these are not FDA-approved. While our research has promising early results, the study is ongoing. That said, it couldn’t hurt if people wanted to add more fresh white button mushrooms to their everyday diet.” 

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Every U.S. Rice Sample Tested Shows Arsenic, Cadmium, or Lead 

Be smart about the rice you consume and how you prepare it to reduce your loved ones’ intake of potentially dangerous heavy metals. 

United States: A new study by Healthy Babies, Bright Futures has uncovered that many rice brands sold in U.S. supermarkets—especially in cities like New York and Miami—contain measurable and potentially dangerous levels of heavy metals. Every single rice sample tested had detectable arsenic, with one-quarter exceeding FDA limits set for infant rice cereal, as reported by HealthDay. 

Infant Rules Don’t Apply to All 

Although the FDA implemented a maximum arsenic level for infant rice cereal in 2021, no such rule exists for regular rice consumed by millions—including toddlers and young children. Researchers stress this loophole as a public health concern. 

Major Brands, Major Findings 

The report tested rice from 145 brands including Trader Joe’s, Ben’s, and Goya. Results showed heavy metal concentrations ranging from 63 to 188 parts per billion (ppb), with some samples reaching as high as 240 ppb. Arsenic was the most commonly found, followed by cadmium. 

Industry Response: Consumers Deserve Reassurance 

The USA Rice Federation acknowledged consumer concerns but insisted current arsenic levels in rice pose no significant public health risk, as reported by HealthDay. 

How to Reduce Your Risk 

The report offers key tips for safer consumption: 

Cook it like pasta: Drown your rice in water (6–10 cups per 1 cup of rice) and let it brew. 

Switch it up: Switch to grains such as quinoa, barley, or couscous, since they contain less heavy metals. 

Pick safer varieties: Look for white rice from California, sushi rice, Thai jasmine, or Basmati rice from India. Stay away from brown rice, Southern-grown white rice and arborio rice imported from Italy (Suggested Alternative: Skip those three varieties as they may contain higher levels of metals). 

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Houston Wastewater Detected Measles Weeks Before Outbreak, Study Finds 

Early detection and prevention of measles can be done by monitoring for the virus in wastewater. 

United States: Measles virus showed up in Houston’s sewage water several weeks before the big measles outbreak happened in Texas in January, according to a new study. 

Early Warning Signs in Wastewater 

Wastewater samples taken on Jan. 7 were found to have measles virus DNA in them, which was reported by scientists in the American Journal of Public Health, as reported by HealthDay. 

According to the researchers, the City of Houston Health Department found and reported two cases of measles in adults not vaccinated for the disease on January 17th. The survey is based on people living in the same areas where the water treatment plants supplied water. 

Measles Resurgence in Texas 

In all, 717 people in Texas had measles as of May 13, reported the Texas Department of State Health Services. Two children who have not been vaccinated have died. 

“With lessons learned from the Houston measles detection event, we are now working with our public health partners to gather data on the current measles outbreak in West Texas,” lead researcher Michael Tisza, an assistant professor of molecular virology and microbiology at Baylor College of Medicine in Houston, said in a news release.  

“Our program has been monitoring measles in wastewater from those sites as well, hoping the information can help officials get ahead of this virus,” Tisza said. 

The sampled Houston treatment plans help more than 218,000 people, according to the researchers. 

Researchers found that testing wastewater before an outbreak revealed that these methods can prepare officials for an infectious disease. 

Wastewater Testing: A Promising Public Health Tool 

“Systematically sequencing the genetic material in wastewater reveals dynamic changes in human viruses circulating in a community,” senior researcher Anthony Maresso, chair of molecular virology and microbiology at Baylor, said in a news release. 

“Importantly, analyzing these viral changes in wastewater can improve our understanding of outbreaks and transmission and inform public health preparedness, just as one uses meteorological data to better understand and predict weather patterns to anticipate potentially dangerous conditions,” Maresso said. 

According to the researchers, there had not been any measles viruses found in any of the 821 wastewater samples collected in Houston in the past 31 months. 

“Because no other cases have been reported and the detections occurred in the same area where the travelers resided, it is reasonable to assume that the measles signal detected in wastewater is from the two infected cases, which underscores the high sensitivity of the method,” Maresso said. 

Vaccination Still the Best Defense 

Co-researcher Eric Boerwinkle, dean of the UTHealth Houston School of Public Health, said that “this work underscores the ability of sophisticated wastewater analyses to serve as an early detection system benefitting public health, healthcare, and communities in preventing a measles outbreak in Houston.” 

If they haven’t already, Boerwinkle advised individuals to acquire the measles vaccine, as reported by HealthDay. 

The best way to stop the contagion of measles is the MMR vaccine, since it has already proven to be both safe and effective. 

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Health

Your Smartphone Might Predict How Well You Recover from Injury 

With more smartphone data, there will be better ways to predict and guide recovery in orthopedics. 

United States: According to a study published on May 9 in the Journal of Bone & Joint Surgery, smartphone data — including step count, walking speed, and gait — can predict how well someone recovers from bone or hip injuries. The findings suggest that mobility patterns before an injury may offer powerful insights into a patient’s post-surgical progress, as reported by HealthDay. 

Data That Speaks Volumes 

The study, led by Dr. Brian Shear at the University of Maryland Medical Center, followed 107 adults who had previously undergone surgery for a broken leg or hip. Using data from participants’ Apple iPhones, researchers analyzed their pre-injury activity levels — specifically, their steps, speed, and gait — and compared it with their recovery progress. 

Patients who were more active before their injury tended to recover faster and return to mobility more easily. “This novel approach has the power to reshape how orthopedic care is delivered,” Dr. Shear explained. 

A New Era of Personalized Rehab 

The study found that patients with higher daily step counts before their injury had better recovery outcomes. Likewise, those with faster walking speeds and consistent gait patterns pre-injury also healed more effectively — highlighting the predictive value of everyday mobility metrics. 

With this knowledge, doctors are able to plan treatments better, detect possible issues in patients’ progress earlier, and give patients more precise timelines for recovery. 

Expanding the Technology’s Use 

Senior researcher Nathan O’Hara, associate professor at the University of Maryland School of Medicine, announced plans to broaden the study’s scope to include other areas of orthopedics like sports medicine, joint replacement, and shoulder or foot surgery, as reported by HealthDay. 

An app is also under development to support this initiative, with multicenter clinical trials expected to begin later this year. 

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