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Immune Changes in Pregnancy: 3 Ways It Protects Against Long COVID

Immune Changes in Pregnancy May Guard Against Long COVID 

United States: A research study indicates pregnancy potentially shields women from long COVID development. 

Recent research published in Nature Communications showed that women who contracted COVID-19 during pregnancy had reduced probabilities between 14% to 30% of establishing chronic symptoms after infection, as reported by HealthDay. 

Pregnancy and Long COVID: A Surprising Protective Effect

New research brings hope by revealing a potential silver lining for women who contracted COVID-19 during pregnancy. A study published in Nature Communications suggests that immune changes in pregnancy may protect women from developing long COVID symptoms, offering a unique insight into how pregnancy could impact virus outcomes.

The research observed a 14% to 30% reduced risk for long COVID in pregnant women, making this an important discovery in the ongoing fight against post-COVID complications.

Immune Changes in Pregnancy May Guard Against Long COVID 
Immune Changes in Pregnancy May Guard Against Long COVID 

Large-Scale Data Supports Findings 

Lead researcher Dr. Chengxi Zang from Weill Cornell Medicine New York City observed that pregnant women who contracted SARS-CoV-2 had a lower risk of long COVID symptoms compared to women who were not pregnant with COVID-19 infections. Zang made this statement in a news release. 

The research team accessed actual healthcare record data from two major computerized medical databases called PCORNet and N3C. 

Healthcare records spanning from March 2020 to June 2023 included information about the 72,000 pregnant women who contracted COVID. The researchers studied a group of 208,000 non-pregnant women who had COVID during the same period as their pregnant cohort. 

People generally experience Long COVID symptoms during the weeks following their first COVID-19 infection. According to the U.S. Centers for Disease Control and Prevention, long COVID symptoms present diverse manifestations and often persist between months to years. 

Among 2,856 pregnant women studied during the COVID-19 pandemic, only 16 experienced symptoms of long-term COVID, whereas 19 of 100 women who were not pregnant developed the condition. 

Research shows pregnant women from particular demographic groups faced higher vulnerability to developing long COVID symptoms. 

Demographic Disparities Still Present 

Black women and women 35 or above and those with obesity developed long COVID while pregnant, according to data findings. Women who were pregnant maintained a lower risk for long-term COVID than comparable women who did not carry a child. 

“Further research on factors such as inequitable healthcare access, socioeconomic factors and structural racism may help us understand the elevated long COVID risk in these groups and find ways to protect them,” Zang said. 

Pregnancy transforms how immune and inflammatory systems function, which might decrease the possibility of developing long COVID, according to Zang. 

Immune Changes in Pregnancy May Guard Against Long COVID 
Immune Changes in Pregnancy May Guard Against Long COVID 

A Path Toward Prevention? 

Research through studying pregnant women could supply scientists with data to develop approaches that prevent long COVID onset, as reported by HealthDay. 

“The observed risk differences in this analysis suggest future dedicated studies of long COVID in pregnant individuals are needed,” Zang said. 

What is Long COVID and Why Does It Matter?


Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), refers to a range of symptoms that persist weeks or months after the initial COVID-19 infection. These symptoms can include fatigue, brain fog, shortness of breath, chest pain, and more, severely impacting quality of life.

According to the U.S. Centers for Disease Control and Prevention (CDC), long COVID can affect people of any age, regardless of how mild or severe their original infection was.

The Study: Large-Scale Data Offers Valuable Insights


This compelling study was led by Dr. Chengxi Zang at Weill Cornell Medicine in New York City. Researchers accessed data from two major health databases — PCORNet and N3C, analyzing electronic health records from March 2020 to June 2023.

The study, which analyzed data from over 72,000 pregnant women, offers a deeper understanding of how immune changes in pregnancy may contribute to reduced long COVID risks compared to non-pregnant women.

Significantly Lower Risk for Pregnant Women


Among the 2,856 pregnant women monitored closely during the study, only 16 developed long COVID symptoms.

In contrast, 19 out of every 100 non-pregnant women developed long COVID. This suggests that physiological changes during pregnancy, particularly in the immune system, may offer natural protection against long-term complications of COVID-19.

Demographic Disparities: Who is Still at Risk?


While the study’s results are encouraging, certain groups of pregnant women still experienced a higher vulnerability.

Black women, women aged 35 or older, and those with pre-existing obesity were more likely to develop long COVID despite being pregnant. These disparities may reflect broader social, economic, and healthcare inequalities, highlighting the need for focused interventions and research.

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Every U.S. Rice Sample Tested Shows Arsenic, Cadmium, or Lead 

Be smart about the rice you consume and how you prepare it to reduce your loved ones’ intake of potentially dangerous heavy metals. 

United States: A new study by Healthy Babies, Bright Futures has uncovered that many rice brands sold in U.S. supermarkets—especially in cities like New York and Miami—contain measurable and potentially dangerous levels of heavy metals. Every single rice sample tested had detectable arsenic, with one-quarter exceeding FDA limits set for infant rice cereal, as reported by HealthDay. 

Infant Rules Don’t Apply to All 

Although the FDA implemented a maximum arsenic level for infant rice cereal in 2021, no such rule exists for regular rice consumed by millions—including toddlers and young children. Researchers stress this loophole as a public health concern. 

Major Brands, Major Findings 

The report tested rice from 145 brands including Trader Joe’s, Ben’s, and Goya. Results showed heavy metal concentrations ranging from 63 to 188 parts per billion (ppb), with some samples reaching as high as 240 ppb. Arsenic was the most commonly found, followed by cadmium. 

Industry Response: Consumers Deserve Reassurance 

The USA Rice Federation acknowledged consumer concerns but insisted current arsenic levels in rice pose no significant public health risk, as reported by HealthDay. 

How to Reduce Your Risk 

The report offers key tips for safer consumption: 

Cook it like pasta: Drown your rice in water (6–10 cups per 1 cup of rice) and let it brew. 

Switch it up: Switch to grains such as quinoa, barley, or couscous, since they contain less heavy metals. 

Pick safer varieties: Look for white rice from California, sushi rice, Thai jasmine, or Basmati rice from India. Stay away from brown rice, Southern-grown white rice and arborio rice imported from Italy (Suggested Alternative: Skip those three varieties as they may contain higher levels of metals). 

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News

Houston Wastewater Detected Measles Weeks Before Outbreak, Study Finds 

Early detection and prevention of measles can be done by monitoring for the virus in wastewater. 

United States: Measles virus showed up in Houston’s sewage water several weeks before the big measles outbreak happened in Texas in January, according to a new study. 

Early Warning Signs in Wastewater 

Wastewater samples taken on Jan. 7 were found to have measles virus DNA in them, which was reported by scientists in the American Journal of Public Health, as reported by HealthDay. 

According to the researchers, the City of Houston Health Department found and reported two cases of measles in adults not vaccinated for the disease on January 17th. The survey is based on people living in the same areas where the water treatment plants supplied water. 

Measles Resurgence in Texas 

In all, 717 people in Texas had measles as of May 13, reported the Texas Department of State Health Services. Two children who have not been vaccinated have died. 

“With lessons learned from the Houston measles detection event, we are now working with our public health partners to gather data on the current measles outbreak in West Texas,” lead researcher Michael Tisza, an assistant professor of molecular virology and microbiology at Baylor College of Medicine in Houston, said in a news release.  

“Our program has been monitoring measles in wastewater from those sites as well, hoping the information can help officials get ahead of this virus,” Tisza said. 

The sampled Houston treatment plans help more than 218,000 people, according to the researchers. 

Researchers found that testing wastewater before an outbreak revealed that these methods can prepare officials for an infectious disease. 

Wastewater Testing: A Promising Public Health Tool 

“Systematically sequencing the genetic material in wastewater reveals dynamic changes in human viruses circulating in a community,” senior researcher Anthony Maresso, chair of molecular virology and microbiology at Baylor, said in a news release. 

“Importantly, analyzing these viral changes in wastewater can improve our understanding of outbreaks and transmission and inform public health preparedness, just as one uses meteorological data to better understand and predict weather patterns to anticipate potentially dangerous conditions,” Maresso said. 

According to the researchers, there had not been any measles viruses found in any of the 821 wastewater samples collected in Houston in the past 31 months. 

“Because no other cases have been reported and the detections occurred in the same area where the travelers resided, it is reasonable to assume that the measles signal detected in wastewater is from the two infected cases, which underscores the high sensitivity of the method,” Maresso said. 

Vaccination Still the Best Defense 

Co-researcher Eric Boerwinkle, dean of the UTHealth Houston School of Public Health, said that “this work underscores the ability of sophisticated wastewater analyses to serve as an early detection system benefitting public health, healthcare, and communities in preventing a measles outbreak in Houston.” 

If they haven’t already, Boerwinkle advised individuals to acquire the measles vaccine, as reported by HealthDay. 

The best way to stop the contagion of measles is the MMR vaccine, since it has already proven to be both safe and effective. 

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Health

Your Smartphone Might Predict How Well You Recover from Injury 

With more smartphone data, there will be better ways to predict and guide recovery in orthopedics. 

United States: According to a study published on May 9 in the Journal of Bone & Joint Surgery, smartphone data — including step count, walking speed, and gait — can predict how well someone recovers from bone or hip injuries. The findings suggest that mobility patterns before an injury may offer powerful insights into a patient’s post-surgical progress, as reported by HealthDay. 

Data That Speaks Volumes 

The study, led by Dr. Brian Shear at the University of Maryland Medical Center, followed 107 adults who had previously undergone surgery for a broken leg or hip. Using data from participants’ Apple iPhones, researchers analyzed their pre-injury activity levels — specifically, their steps, speed, and gait — and compared it with their recovery progress. 

Patients who were more active before their injury tended to recover faster and return to mobility more easily. “This novel approach has the power to reshape how orthopedic care is delivered,” Dr. Shear explained. 

A New Era of Personalized Rehab 

The study found that patients with higher daily step counts before their injury had better recovery outcomes. Likewise, those with faster walking speeds and consistent gait patterns pre-injury also healed more effectively — highlighting the predictive value of everyday mobility metrics. 

With this knowledge, doctors are able to plan treatments better, detect possible issues in patients’ progress earlier, and give patients more precise timelines for recovery. 

Expanding the Technology’s Use 

Senior researcher Nathan O’Hara, associate professor at the University of Maryland School of Medicine, announced plans to broaden the study’s scope to include other areas of orthopedics like sports medicine, joint replacement, and shoulder or foot surgery, as reported by HealthDay. 

An app is also under development to support this initiative, with multicenter clinical trials expected to begin later this year. 

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