FDA approves AstraZeneca’s Truqap for breast cancer

FDA approves AstraZeneca's Truqap for breast cancer | Credits: AP
FDA approves AstraZeneca's Truqap for breast cancer | Credits: AP

United States: Breast cancer now has a new treatment in the United States. On Thursday, the US Food and Drug Administration (FDA) approved Truqap – a production by AstraZeneca – as an option for the treatment of patients with most types of breast cancer.

According to the reports by news agency Reuters, this latest drug, Truqap (chemically known as capivasertib), is in combination with an older drug. The green light by the FDA allows physicians across the United States to use the drug, in combination with the older cancer treatment, named faslodex, by the British drugmaker.

The experts have suggested that the Truqap is the new entry in the market of breast cancer treatments – which presently include ‘Daiichi Sankyo’s Enhertu’ by AstraZeneca and ‘Trodelvy’ by Gilead.

Patients with which cancer type can use the medicine?

Medical experts have suggested that the drug Truqap can be used by adult patients with the HR-positive/HER2-negative subtype of breast cancer. Along with this, the FDA has stated that patients with tumors of one of three genes – PIK3CA, AKT1 or PTEN, can also use the medicine.

The medicine improved the time patients with altered gene tumors lived without their condition getting worse by 7.3 months in a final-stage study, Reuters informed.

What is Truqap?

Medical experts have asserted that the drug is known as an AKT inhibitor and it targets the AKT1 gene mutation. It is to be noted that the mutation is responsible for the tumor’s growth as well as proliferation in the host’s body.

Credits: Shutterstock Image

The Food and Drug Administration has further underscored that this disease is also effective for patients whose tumor has returned or have become worse after the hormone-based therapy.

While emphasizing the common side-effects of the drug, the health regulations stated that a patient can witness side effects, including diarrhea, decreased hemoglobin, nausea, fatigue, and others.

Breast cancer – the most common cancer diagnosed in the US

The American Cancer Society has claimed that among women breast cancer is the most diagnosed cancer type among women in the United States. Besides this, it is also the second leading cause of death from cancer among women population.

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